Supporting gut health is all the rage – especially when it comes to your skin (thanks to the gut-skin connection!). Because of this, you’ve probably heard of colostrum supplements, and wonder if colostrum benefits could aid in supporting your sensitive skin (and gut).
But here’s the thing that influencers won’t tell you – there’s colostrum and then there’s immunoglobulin supplements, which are an even better, more helpful version of colostrum.
And if you are dairy-free – then you really need to know about immunoglobulins!
Let’s talk about what colostrum is, how it compares to immunoglobulin supplements, and why you might want to consider one over the other—especially if you’re dealing with histamine issues, digestive and gut discomfort, or food sensitivity.
We'll also explore how our HistaGut Relief IgG dairy-free immunoglobulin supplement supports your sensitive skin and gut goals.
What Is Colostrum?
Colostrum is the first form of milk produced by mammals (including cows) in the first few days after giving birth. It’s rich in antibodies, growth factors, and nutrients that help build a newborn’s immune system.
Bovine colostrum, commonly used in supplements, is praised for its immune-boosting and gut-supportive properties. Some of the key colostrum benefits include:
- Supporting gut lining integrity
- Promoting immune function
- Assisting with nutrient absorption
However, not all colostrum products are created equal. Many colostrum supplements are not always standardized, meaning the levels of immunoglobulins in the product can fluctuate greatly by brand and even by individual batches (of the same product).
Even when a colostrum supplement is standardized, it will never contain 100% immunoglobulins (which is the key component that is responsible for the health benefits companies love to talk about). The most a colostrum product is standardized to would be 40%.
For example – if a colostrum supplement contains 1000mg of colostrum that’s standardized to 40%, each serving only contains 400mg of IgGs.
To make matters worse, if no standardization of immunoglobulins is listed on the nutrition label, then you have no idea how much immunoglobulins are in that product.
Additionally, colostrum is not dairy-free. In fact, it contains dairy, which can be a problem for someone who is dairy intolerant or even has a dairy allergy.
Understanding Immunoglobulin Supplements
Immunoglobulin supplements (often listed as IgG or serum-derived bovine immunoglobulins) are concentrated proteins that play a vital role in your immune system. While they can be found in colostrum, immunoglobulins are also found (and can be isolated from) the serum of cows.
Unlike colostrum, immunoglobulin supplements are typically free of dairy, lactose and casein.
They are specifically formulated to bind with pathogens and toxins in the gut as they pass through.
Benefits of Immunoglobulin Supplements:
- Help manage and boost the strength of your gut
- Neutralize pathogens and unfriendly gut bugs
- Reduce occasional bloating, gas, and soft poops
- Bind to trouble-making toxins (like Lipopolysaccharides, aka. LPS) that can increase inflammation
- Support immune balance
- May reduce issues with histamine intolerance
Because they are more concentrated and standardized, immunoglobulin supplements work better and more efficiently compared to colostrum powder.
This is a big deal because IgGs give you “more bang for your buck”!
Immunoglobulin supplements have a more targeted effect because of their higher potency.
Colostrum vs. Immunoglobulin Supplements: Key Differences
While colostrum and immunoglobulins both support your gut health (which benefits your energy level, sensitive skin, and wellbeing), they do so in different ways.
| Feature | Colostrum | Immunoglobulin Supplements |
| Source | First milk from cows after birth (❌ contains dairy) | Serum-derived bovine immunoglobulin (✅ dairy-free) |
| Potency | ❌ Varies by brand, but reduced due to lower concentration | ✅ Higher because of consistent concentration |
| Immune Support | ❌ General immune support | ✅ Targeted immune regulation |
| Gut Barrier Support | ❌ Indirect | ✅ Direct (binds pathogens/toxins) |
| Standardization | ❌ Often not standardized | ✅ Always standardized |
Why Immunoglobulin Supplements May Be a Better Choice
If you're struggling with:
- Histamine intolerance complaints
- Leaky gut
- Sensitive to food (especially if IgG reactions are increasing)
- Gut issues like occasional gas, bloating, and belching
- Soft, loose poops 💩
- Post-infectious gut issues (ie. post-food poisoning, stomach bug)
... you may find that a targeted immunoglobulin supplement is more effective than a generic colostrum product.
Unlike colostrum, immunoglobulin supplements provide concentrated, high-potency IgGs to support histamine balance, sensitive skin, and gut imbalances!
A Smarter Option: HistaGut Relief IgG
HistaGut Relief IgG is a helpful dairy-free immunoglobulin supplement that bolsters gut and immune support—without unnecessary fillers, allergens, or variability in dosage.
Because it is nutritionist-formulated specifically for your needs, HistaGut Relief IgG:
- Delivers 2,000mg of serum-derived bovine immunoglobulin (standardized IgG)
- Supports the gut lining and mucosal immune system
- Helps bind toxins (like LPS), antigens, and histamine byproducts
- Free from dairy, gluten, soy, and GMOs
And though it has a fascinating capacity to bind to toxins in the gut, it cannot bind to medication, supplements, or food. That means you can take it when you need it!
How to Spot Poor-Quality Colostrum or IgG Products
When choosing between colostrum and a high-quality immunoglobulin supplement like HistaGut Relief IgG, be wary of products that:
- Don’t list exact immunoglobulin concentrations
- Contain artificial additives or fillers
- Use proprietary blends that don’t reveal how many grams of immunoglobulins are in the product
It’s best to stick with a product that offers transparency, third-party testing, and concentrated formulations—like HistaGut Relief IgG.
3 Action Steps to Support Your Gut and Immune Health
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Understand what you’re taking: Learn the difference between colostrum and immunoglobulin supplements. While colostrum offers general immune support, immunoglobulins like IgG provide targeted action.
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Choose a high-quality product: Opt for a supplement that is standardized, well-tolerated, and concentrated, like HistaGut Relief IgG.
- Listen to your body: If you struggle with histamine-related complaints--it may be time to add concentrated IgGs to boost the power of your histamine intolerance supplement protocol.
Final Thoughts on Immunoglobulin Colostrum Benefits
There’s no doubt that there are real colostrum benefits…
But if you can’t eat dairy…
Or you’d prefer a more potent gut and immune support option—immunoglobulin supplements like HistaGut Relief IgG offer a more trusted, helpful and reliable option.
If you’re ready to try a science-backed, nutritionist-formulated supplement to help balance the gut-skin connection, try HistaGut Relief IgG to take your first step towards supporting calmer skin and a stronger gut!